This document aims at giving advice on the quality of water to be used in the preparation of antigens usedThis document aims at giving advice on the quality of water to be used in the preparation of antigens usedin the manufacturing process of vaccines. It takes into account the new European Pharmacopoeiamonographs, which were introduced in 2002 as well as the QWP Note for Guidance on the Quality ofWater for pharmaceutical use, which was adopted by the CPMP in November 2001